Gefördert durch:

Prof. Dr. Ralf Reski


Institut für Biologie II (Pflanzenbiotechnologie), Universität Freiburg

Tel:      +49 761 203 6969



Opposing scientific mainstream I have developed the moss Physcomitrella patens to a model species for evolutionary developmental biology, systems biology, and synthetic biology. Four of my scientific achievements with this species are the first identification of a gene function in plants by gene targeting, first functional identification of a protein pivotal for division of any eukaryotic organelle, first complete genome sequence of a lower plant, and identification of a novel mechanism for eukaryotic gene regulation. Further, I am co-inventor of the Moss Bioreactor.

We are interested in the identification of novel biochemical pathways, unravelling the signalling events leading to developmental decisions and to protection against abiotic stress, and in the production of complex biopharmaceuticals in the Moss Bioreactor.


Short CV


10 ausgewählte Publikationen:

  • A single homeobox gene triggers phase transition, embryogenesis, and asexual reproduction.
    Horst NA, Katz A, Pereman I, Decker EL, Ohad N, Reski R. (2016).
    Nat Plants 2, 15209.
  • Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss.
    Schuessele C, Hoernstein SN, Mueller SJ, Rodriguez-Franco M, Lorenz T, Lang D, Igloi GL, Reski R (2016)
    New Phytol. 209, 1014-1027.
  • Moss-made pharmaceuticals: from bench to bedside.
    Reski R, Parsons J, Decker EL (2015).
    Plant Biotechnol J. 13, 1191-1198.
  • Stomatal guard cells co-opted an ancient ABA-dependent desiccation survival system to regulate stomatal closure.
    Lind C, Dreyer I, López-Sanjurjo EJ, von Meyer K, Ishizaki K, Kohchi T, Lang D, Zhao Y, Kreuzer I, Al-Rasheid KA, Ronne H, Reski R, Zhu JK, Geiger D, Hedrich R (2015).
    Current Biology 25, 928-935.
  • Insights from the cold transcriptome of Physcomitrella patens: global specialization pattern of conserved transcriptional regulators and identification of orphan genes involved in cold acclimation.
    Beike AK, Lang D, Zimmer AD, Wüst F, Trautmann D, Wiedemann G, Beyer P, Decker EL, Reski R. (2015).
    New Phytologist 205, 869-881.
  • Plasma membrane-targeted PIN proteins drive shoot development in a moss.
    Bennett TA, Liu MM, Aoyama T, Bierfreund NM, Braun M, Coudert Y, Dennis RJ, O'Connor D, Wang XY, White CD, Decker EL, Reski R, Harrison CJ0 (2014).
    Current Biology 24, 2776-2785.
  • Quantitative analysis of the mitochondrial and plastid proteomes of the moss Physcomitrella patens reveals protein macrocompartmentation and microcompartmentation.
    Mueller SJ, Lang D, Hoernstein SN, Lang EG, Schuessele C, Schmidt A, Fluck M, Leisibach D, Niegl C, Zimmer AD, Schlosser A, Reski R (2014).
    Plant Physiology 164, 2081-2095.
  • A gene responsible for prolyl-hydroxylation of moss-produced recombinant human erythropoietin. Parsons J, Altmann F, Graf M, Stadlmann J, Reski R, Decker EL.(2013).
    Sci Rep. 3, 3019.
  • Transcriptional control of gene expression by microRNAs.
    Khraiwesh B, Arif MA, Seumel GI, Ossowski S, Weigel D, Reski R, Frank W (2010).
    Cell 140, 111-122.
  • The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants.
    Rensing SA, Lang D, Zimmer AD, Terry A, Salamov A, Shapiro H, Nishiyama T, Perroud PF, Lindquist EA, Kamisugi Y, Tanahashi T, Sakakibara K, Fujita T, Oishi K, Shin-I T, Kuroki Y, Toyoda A, Suzuki Y, Hashimoto S, Yamaguchi K, Sugano S, Kohara Y, Fujiyama A, Anterola A, Aoki S, Ashton N, Barbazuk WB, Barker E, Bennetzen JL, Blankenship R, Cho SH, Dutcher SK, Estelle M, Fawcett JA, Gundlach H, Hanada K, Heyl A, Hicks KA, Hughes J, Lohr M, Mayer K, Melkozernov A, Murata T, Nelson DR, Pils B, Prigge M, Reiss B, Renner T, Rombauts S, Rushton PJ, Sanderfoot A, Schween G, Shiu SH, Stueber K, Theodoulou FL, Tu H, Van de Peer Y, Verrier PJ, Waters E, Wood A, Yang L, Cove D, Cuming AC, Hasebe M, Lucas S, Mishler BD, Reski R, Grigoriev IV, Quatrano RS, Boore JL. (2008).
    Science 319, 64-69.